9β,11β-Epoxy Eplerenone

Chemical Name:9β,11β-Epoxy Eplerenone
Synonyms:(2’R,4aS,4bS,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,5′-dioxo-3,4,4a,4′,5a,5′,6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3’H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2′-furan]-10-carboxylate
Molecular Formula:C₂₄H₃₀O₆
Molecular Weight:414.49
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:9β,11β-Epoxy Eplerenone is an impurity of Eplerenone (E588775), a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References:de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.