CAS:915095-87-3|(2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone

CAS:915095-87-3|(2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone

Catalogue Number:C371265
Chemical Name:(2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone
CAS Number:915095-87-3
Molecular Formula:C₁₇H₁₄ClIO₃
Appearance:Off-White to Pale Beige Solid
Melting Point:109-113ºC
Molecular Weight:428.65
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone is an intermediate of Empagliflozin (E521510) which is a potent and selective SGLT-2 inhibitor that improves glycaemic control syndrome in diabetic rats.
References:Wang, X., et al.: Org. Lett., 16, 4090 (2014);
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