CAS:162012-67-1|4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline

Catalogue Number:C376250
Chemical Name:4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline
Synonyms:N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine; (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine
CAS Number:162012-67-1
Molecular Formula:C₁₄H₇ClF₂N₄O₂
Appearance:Yellow to Dark Yellow Solid
Melting Point:240 – 243°C
Molecular Weight:336.68
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly, Sonicated)
Category:Building Blocks; Miscellaneous;
Applications:4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
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