CAS:52669-92-8|4-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone

Catalogue Number:C376580
Chemical Name:4-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone
Synonyms:4-[4-(p-Chlorophenyl)-2,5,6-trihydropyridino]-4′-fluorobutyrophenone; HPTP; Dehydrate Haloperidol
CAS Number:52669-92-8
Molecular Formula:C₂₁H₂₁ClFNO
Appearance:Pale Yellow Solid
Melting Point:97 – 100°C
Molecular Weight:357.85
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone is a dehydrated metabolite of haloperidol that can be biotransfomed by humans to Haloperidol pyridinium (HPP+), a potential neurotoxic found in the brain.
References:Usuki, E., et. al.: Neurotoxicity Res., 4, 51 (2002)
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