CAS:1496552-50-1|Chloro (R)-Phosphoryl Sofosbuvir

Catalogue Number:C379305
Chemical Name:Chloro (R)-Phosphoryl Sofosbuvir
CAS Number:1496552-50-1
Molecular Formula:C₂₂H₂₉ClN₃O₉P
Molecular Weight:545.91
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Chloro (R)-Phosphoryl Sofosbuvir can be used to synthesize nucleoside phosphoramidate compounds and 2′-chloro nucleotide analogs that are potential treatment of hepatitis C virus (HCV) infection. Chloro (R)-Phosphoryl Sofosbuvir is also a phosphorus epimer of Chloro Sofosbuvir (C382095) and a related compound of Sofosbuvir (P839640).
References:Simmons, B. L., et al.: PCT Int. Appl. WO 2016064797 A1 20160428 (2016); Gosselin, G., et al.: PCT Int. Appl. WO 2014058801 A1 20140417 (2014)
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