CAS:53786-28-0|5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone

Catalogue Number:C379725
Chemical Name:5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone
Synonyms:Des[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone; 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine; 5-Chloro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-(piperidin-4-yl)-1H-benzimidazol-2(3H)-one; 5-Chloro-1-piperidin-4-yl-1,3-dihydrobenzimidazol-2-one; R 29676
Impurity:Domperidone EP Impurity A
CAS Number:53786-28-0
Molecular Formula:C₁₂H₁₄ClN₃O
Appearance:White to Off-White Solid
Melting Point:225-228°C
Molecular Weight:251.71
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone (Domperidone EP Impurity A) is a metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).
References:Meuldermans, W. et al.: Eur. J. Drug Metab. Pharmacokin., 6, 49 (1981); Simard, C. et al.: Xenobiotica, 34, 1013 (2004);
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