CAS:492444-39-0|4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline

Catalogue Number:C380750
Chemical Name:4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline
Synonyms:4-Chloro-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosutinib Impurity:Impurity:Bosutinib Impurity:CAS Number:492444-39-0
Molecular Formula:C₁₉H₂₃ClN₄O₂
Appearance:White to Off-White Solid
Melting Point:173 – 175ºC
Molecular Weight:374.86
Storage:-20°C, Hygroscopic
Solubility:Acetonitrile (Slightly), Chloroform (Slightly)
Stability
Hygroscopic
Category:Building Blocks;
Applications:4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline is a useful reagent to prepare benzofuranyl derivatives for treating solid tumours. It is also an impurity of Bosutinib.
References:Hennequin, L. F. A. PCT Int. Appl. (2003), WO 2003047585 A1 20030612 (2003); Hennequin, L. F. A., Gibson, K. H., Foote, K. M. PCT Int. Appl. WO 2003047582 A1 20030612 (2003)
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