CAS:23964-56-9|3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene

Catalogue Number:C380873
Chemical Name:3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
Synonyms:Methyl 3-(2-chloropropanoylamino)-4-methyl-2-thiophenecarboxylate
CAS Number:23964-56-9
Molecular Formula:C₁₀H₁₂ClNO₃S
Appearance:White Solid
Molecular Weight:261.73
Solubility:Dichloromethane, Dimethylsulfoxide, Methanol
Category:Building Blocks; Miscellaneous;
Applications:3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.
References:Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)
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