Catalogue Number:C381385
Chemical Name:N-[4-[(7-Chloro-4-quinolinyl)amino]pentyl]-N-ethyl-carbamic Acid 2,2,2-Trichloroethyl Ester
CAS Number:1026601-42-2
Molecular Formula:C₁₉H₂₃Cl₄N₃O₂
Molecular Weight:467.22
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-[4-[(7-Chloro-4-quinolinyl)amino]pentyl]-N-ethyl-carbamic Acid 2,2,2-Trichloroethyl Ester is an intermediate used in the synthesis of Desethyl Chloroquine (D288735), which is the major product of the stereoselective human metabolism of Chloroquine, used for the therapy and prevention of malaria.
References:Essien, E., et al.: J. Pharm. Pharmacol., 38, 543 (1986), Akintonwa, A., et al.: Ther. Drug Monit., 10, 147 (1988), Boelaert, J., et al.: AIDS, 15, 2205 (2001), Basco, L., et al.: Antimicrob. Agents Chemother., 47, 1391 (2003)
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CAS:1026601-42-2|N-[4-[(7-Chloro-4-quinolinyl)amino]pentyl]-N-ethyl-carbamic Acid 2,2,2-Trichloroethyl Ester
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