CAS:1377503-12-2|4-Chloro-2-hydroxyphenylboronic acid pinacol ester

Catalogue Number:C421998
Chemical Name:4-Chloro-2-hydroxyphenylboronic acid pinacol ester
Synonyms:5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
CAS Number:1377503-12-2
Molecular Formula:C₁₂H₁₆BClO₃
Appearance:White to Off-White Solid
Molecular Weight:254.52
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Stable under recommended storage conditions., Stable Under Recommended Storage C
Category:Building Blocks;
Applications:4-Chloro-2-hydroxyphenylboronic acid pinacol ester is a building block which has seen use in the preparation of 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridin-3-ylacetic acid derivs. for treatment of HIV infection, and in the preparation of disubstituted pyridazine analogs useful in the treatment of SMN deficiency related diseases.
References:Bell, A. S.; et al.: WO 2012066442 (2012). Cheung, A.; et al.: WO 2014028459 (2014).
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