CAS:380844-49-5|1-Chloro-1-desmethylpiperazinyl-bosutinib

CAS:380844-49-5|1-Chloro-1-desmethylpiperazinyl-bosutinib

Catalogue Number:C423040
Chemical Name:1-Chloro-1-desmethylpiperazinyl-bosutinib
Synonyms:7-(3-Chloropropoxy)-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile
CAS Number:380844-49-5
Molecular Formula:C₂₁H₁₈Cl₃N₃O₃
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:206 – 209°C
Molecular Weight:466.74
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly, Sonicated), DMSO (Slightly)
Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-Chloro-1-desmethylpiperazinyl-bosutinib is a useful intermediate in the green preparation of the anti-tumor agent Bosutinib (B676095). It is a COVID19-related research product.
References:Mao, Y., et al.: Synthesis, 47, 3133 (2015); Chen, H., et al.: Zhongguo Yiyao Gongye Zazhi, 44, 1086 (2013); Yin, X. J., et al.: Molecules, 4261 (2010)
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