Emtricitabine 5-O-Sulfate-13C,15N2

Chemical Name:Emtricitabine 5-O-Sulfate-13C,15N2
Synonyms:4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone 5-O-Sulfate-13C,15N2; (-)-2’,3’-Dideoxy-5-fluoro-3’-thiacytidine 5-O-Sulfate-13C,15N2; (-)-2′-Deoxy-5-fluoro-3′-thiacytidine 5-O-Sulfate-13C,15N2; BW 1592 5-O-Sulfate-13C,15N2; BW 524W91 5-O-Sulfate-13C,15N2; Coviracil 5-O-Sulfate-13C,15N2; Emtriva 5-O-Sulfate-13C,15N2; (-)-FTC 5-O-Sulfate-13C,15N2
Molecular Formula:C₇¹³CH₁₀FN¹⁵N₂O₆S₂
Molecular Weight:330.29
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:Emtricitabine 5-O-Sulfate-13C,15N2 is the isotope labelled analog of Emtricitabine 5-O-Sulfate (E525080); a metabolite of Emtricitabine (E525000) which is a reverse transcriptase inhibitor and an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.
References:FASEB J., 13, 1511 (1999); Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992); Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996); Feng, J.Y., et al.: . Dis., 182, 599 (2000)
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