CAS:5428-61-5|N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine

Catalogue Number:C542615
Chemical Name:N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
Synonyms:5-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
CAS Number:5428-61-5
Molecular Formula:C₁₈H₂₆ClN₃
Appearance:Dark Orange to Dark Brown Oil
Molecular Weight:319.87
Storage:-20°C
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine is a metabolite of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ.
References:Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),
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