CAS:145915-58-8|CGP 52411

Catalogue Number:C583570
Chemical Name:CGP 52411
Synonyms:5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione; DAPH; 4,5-Dianilinophthalimide
CAS Number:145915-58-8
Molecular Formula:C₂₀H₁₅N₃O₂
Appearance:Yellow to Dark Yellow Solid
Melting Point:>185°C (dec.)
Molecular Weight:329.35
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.
References:Buchdunger, E., et al.: Proc. Natl. Acad. Sci. U.S.A., 91, 2334 (1994);
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