CAS:23593-71-7|para-Clotrimazole Isomer

Catalogue Number:C587405
Chemical Name:para-Clotrimazole Isomer
Synonyms:1-[(4-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(p-Chloro-α,α-diphenylbenzyl)imidazole; 1-[(p-Chlorophenyl)diphenylmethyl]imidazole; CDD 3532; Clotrimazole Impurity A; Clotrimazole EP Impurity B
Impurity:Clotrimazole EP Impurity B
CAS Number:23593-71-7
Molecular Formula:C₂₂H₁₇ClN₂
Appearance:White to Off-White Solid
Melting Point:138-140°C
Molecular Weight:344.84
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.
References:Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004);
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