CAS:1374640-70-6|CO 1686

Catalogue Number:C633000
Chemical Name:CO 1686
Synonyms:N-[3-[[2-[[4-(4-Acetyl-1-piperazinyl)-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide
CAS Number:1374640-70-6
Molecular Formula:C₂₇H₂₈F₃N₇O₃
Appearance:Off-White Solid
Melting Point:202 – 205°C (dec.)
Molecular Weight:555.55
Storage:-20°C, Inert atmosphere, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CO 1686 is seen as an irreversible epidermal growth factor receptor (EFGR1) kinase inhibitor.
References:Walter, A. et al.: Cancer Disc., 21, 3 (2013);
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