CAS:19286-37-4|Convicine

Catalogue Number:C685095
Chemical Name:Convicine
Synonyms:6-Amino-5-(β-D-glucopyranosyloxy)-2,4(1H,3H)-pyrimidinedione;
CAS Number:19286-37-4
Molecular Formula:C₁₀H₁₅N₃O₈
Appearance:Light Beige to Brown Solid
Melting Point:>210° (dec.)
Molecular Weight:305.24
Storage:-20°C
Solubility:Aqueous Base (Slightly), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Convicine, is a derivative of Vicine (V250005), a pyrimidine glycosides, a precursor of the aglycons divicine and isouramil which is main factors of favism. It is found in faba/fava bean. Also, it is derived from Ethyl Glyoxylate (E918550), which is used as a reagent in the synthesis of a new class of cinnamyl-triazole compounds which can be used as selective inhibitors of human aromatase (cytochrome P 450 19A1)
References:Rizzello, C. G., et al.: Sci. Rep., 6, 32452 (2016); Pulkkinen, M., et al.: Food Chem., 212, 10-19 (2016); McNulty, J., et al.: Bioorg. Med. Chem. Lett., 24, 4586 (2014)
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