(R)-2-Hydroxy-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propanoic Acid

Chemical Name:(R)-2-Hydroxy-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propanoic Acid
Synonyms:(S)-Timolol (Anhydrous) Impurity
Molecular Formula:C₉H₁₃N₃O₅S
Molecular Weight:275.28
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(R)-2-Hydroxy-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propanoic Acid is an impurity of (R)-Timolol (T443695). (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain.
References:Rotmensch, H. et al.: J. Clinical. Pharmacol., 33, 544 (1993); Chiou, G. & Chen. Y., J. Ocular. Pharmacol., 8, 183 (1992); Chiou, G. et al.: J. Ocular. Pharmacol., 6, 23 (1990); Tocco, D. et al.: Drug Met. Disposit., 4, 323 (1976)
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