CAS:132746-60-2|CP 96345

CAS:132746-60-2|CP 96345

Catalogue Number:C781210
Chemical Name:CP 96345
Synonyms:(2S,3S)-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine; (2S-cis)-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine;
CAS Number:132746-60-2
Molecular Formula:C₂₈H₃₂N₂O
Molecular Weight:412.57
Category:Research Tools;
Applications:CP 96345 is a potent and selective non-peptide NK1 receptor antagonist (1,2,3). CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.
References:(1) Snider, et al.: Science, 251. 435 (1991)
(2) Lembeck, et al.: Br. J. Pharmacol. 105, 527 (1992)
(3) Bang, et al.: J. Pharmacol. Exp. Ther. 305 , 31 (2003)
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