CAS:960355-08-2|2-​Chloro-​1-​[2-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyridin-​3-​yl]​-1-propanone

Catalogue Number:C960355
Chemical Name:2-​Chloro-​1-​[2-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyridin-​3-​yl]​-1-propanone
CAS Number:960355-08-2
Molecular Formula:C₁₃H₁₅ClN₂O
Appearance:Light pink solid
Molecular Weight:250.72
Storage:-20°C
Solubility:DMSO
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-​Chloro-​1-​[2-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyridin-​3-​yl]​-1-propanone is an intermediate in the synthesis of AV1013 (2-Amino-1-[2-(1-methylethyl) pyrazolo[1,5-a] pyridin-3-yl]-1-propanone hydrochloride) (A618170), which is a drug candidate for the treatment of neuropathic pain, addiction behavior and drug withdrwal symptoms.
References:Kirk, W. J. et al.: U.S. Pat. Appl. Publ. US 20100324082 A1 20101223 (2010).
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