CAS:90357-51-0|N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide

Catalogue Number:C987585
Chemical Name:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
Synonyms:(±)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide; 2-Methyloxirane-2-carboxylic acid N-(4-Cyano-3-trifluoromethylphenyl)amide;
Impurity:Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity:CAS Number:90357-51-0
Molecular Formula:C₁₂H₉F₃N₂O₂
Appearance:White to Off-White Solid
Melting Point:152-154°C
Molecular Weight:270.21
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References:Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);
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