CAS:404578-37-6|25-​Cyclohexyl-​4′-​O-​de(2,​6-​dideoxy-​3-​O-​methyl-​a-​L-​arabino-​hexopyranosyl)​-​5-​demethoxy-​25-​de(1-​methylpropyl)​-​5-​oxo-avermectin A1a

Catalogue Number:C988228
Chemical Name:25-​Cyclohexyl-​4′-​O-​de(2,​6-​dideoxy-​3-​O-​methyl-​a-​L-​arabino-​hexopyranosyl)​-​5-​demethoxy-​25-​de(1-​methylpropyl)​-​5-​oxo-avermectin A1a
CAS Number:404578-37-6
Molecular Formula:C₄₃H₆₀O₁₁
Appearance:Pale Yellow to Yellow Solid
Melting Point:>140°C (dec.)
Molecular Weight:752.93
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:25-​Cyclohexyl-​4′-​O-​de(2,​6-​dideoxy-​3-​O-​methyl-​a-​L-​arabino-​hexopyranosyl)​-​5-​demethoxy-​25-​de(1-​methylpropyl)​-​5-​oxo-avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals.
References:Eshar, D., et al.: J. Am. Veterin. Med. Association., 241, 1056 (2012); Geis-Asteggiante, L., et al.: J. Chromatograph., 1258, 43 (2012)
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