16β-Methyl-17α,21-Dihydroxypregna-1,4-diene-3,20-dione

Chemical Name:16β-Methyl-17α,21-Dihydroxypregna-1,4-diene-3,20-dione
Synonyms:(8S,9S,10S,13S,14S,16S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-9,10,13,16-tetramethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; Betamethasone Impurity J EP
Impurity
Betamethasone EP Impurity J
CAS Number:18383-24-9
Molecular Formula:C₂₂H₃₀O₄
Molecular Weight:358.47
Category:Building Blocks; Miscellaneous;
Applications:16β-Methyl-17α-Dihydroxypregna-1,4-diene-3,20-dione is an intermediate in the synthesis of 17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione (D434280), a corticoid with the potential for ant-iinflammatory activity.
References:Collins, E. et al.: Proc. Int. Congr. Horm. Steroids, 2nd, 530 (1967); Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),
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