CAS:941685-37-6|(3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile (ent-Ruxolitinib)

Catalogue Number:C988940
Chemical Name:(3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile (ent-Ruxolitinib)
Synonyms:(βS)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
CAS Number:941685-37-6
Molecular Formula:C₁₇H₁₈N₆
Appearance:White Solid
Melting Point:138-143ºC
Molecular Weight:306.37
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile is a newly developed JAK2 inhibitor therapy aimed to improve MPN-associated splenomegaly and systemic symptoms. The opposite enantiomer of Ruxolitinib (R702000).
References:Koppikar, P., et al.: Nature., 489, 155 (2012); Ratcliffe, A.J., et al.: Drug. Discover. Series., 19, 218 (2012);
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com