CAS:372078-46-1|5-Cyclopropyl-1-(1,2-dihydro-2-oxo-5-quinolinyl)-1H-pyrazole-4-carboxylic Acid Methyl Ester

Catalogue Number:C989010
Chemical Name:5-Cyclopropyl-1-(1,2-dihydro-2-oxo-5-quinolinyl)-1H-pyrazole-4-carboxylic Acid Methyl Ester
CAS Number:372078-46-1
Molecular Formula:C₁₇H₁₅N₃O₃
Appearance:Light Brown Solid
Melting Point:206-208°C
Molecular Weight:309.32
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Cyclopropyl-1-(1,2-dihydro-2-oxo-5-quinolinyl)-1H-pyrazole-4-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Zoniporide (Z680000), a potent and selective inhibitor of human sodium-hydrogen exchanger used to protect against cardiac ischemia-reperfusion injury.
References:Dalvie, D., et al.: Drug. Metab. Disposit., 40, 1575 (2012); Dalvie, D., et al.: Drug. Metab. Disposit., 38, 641 (2010);
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