CAS:163597-57-7|3-​Cyano-​4-​isobutyloxythiobenza​mide

Catalogue Number:C990343
Chemical Name:3-​Cyano-​4-​isobutyloxythiobenza​mide
CAS Number:163597-57-7
Molecular Formula:C₁₂H₁₄N₂OS
Molecular Weight:234.32
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-​Cyano-​4-​isobutyloxythiobenza​mide is an impurity in the preparation of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.
References:Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),
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