CAS:1159824-67-5|CZC24832

Catalogue Number:C999000
Chemical Name:CZC24832
Synonyms:5-(2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)pyridine-3-sulfonamide; 5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridinesulfonamide
CAS Number:1159824-67-5
Molecular Formula:C₁₅H₁₇FN₆O₂S
Molecular Weight:364.4
Category:Research Tools;
Applications:CZC24832 is a selective phosphoinositide 3-kinase γ (PI3Kγ) inhibitor. CZC24832 regulates interleukin-17-producing T helper cell (TH17) differentiation by PI3Kγ thus making CZC24832 a potential treatment for inflammatory and autoimmune diseases.
References:Bergamini, G., et. al.: Nat. Chem. Biol., 8, 576 (2012)
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