CAS:3102-56-5|DL-erythro-Dihydrosphingosine

Catalogue Number:D151745
Chemical Name:DL-erythro-Dihydrosphingosine
Synonyms:(2R,3S)-rel-2-amino-1,3-octadecanediol; (±)-erythro-2-amino-1,3-octadecanediol; dl-erythro-Dihydrosphingosine; erythro-C18-Sphinganine; erythro-DL-Sphinganine
CAS Number:3102-56-5
Molecular Formula:C₁₈H₃₉NO₂
Appearance:White to Off-White Solid
Melting Point:>86°C (dec.)
Molecular Weight:301.51
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:Dihydrosphingosine is an inhibitor of protein kinase C. (PKC). Dihydrosphingosine is a novel activator of 3-Phosphinositide-dependent kinase 1. Sphingosine appeared to be a true PDK1 activator.
References:Buehrer, B., et al.: J. Biol. CHem., 267, 3154 (1992); King, C., et al.: J. Biol. Chem., 275, 18108 (2000);
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