CAS:1204219-80-6|Dapagliflozin-D5

Catalogue Number:D185372
Chemical Name:Dapagliflozin-D5
Synonyms:(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol-D5; BMS 512148-D5; (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(ethoxy-D5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
CAS Number:1204219-80-6
Alternate CAS #
461432-26-8
Molecular Formula:C₂₁H₂₀D₅ClO₆
Appearance:White to Off-White Solid
Melting Point:>62°C (dec.)
Molecular Weight:413.9
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Research Tools; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dapagliflozin-D5 is a labelled analog of Dapagliflozin (CAT# D185370), which is a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes.
References:List, J., et al.: Diabetes Care, 32, 650 (2009); Meng, W., et al.: J. Med. Chem., 51, 1145 (2008); Wilding, J., et al.: Diabetes Care, 32, 1656 (2009)
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