CAS:314263-42-8|DCG04

Catalogue Number:D195170
Chemical Name:DCG04
Synonyms:N-[[(2S,3S)-3-(Ethoxycarbonyl)-2-oxiranyl]carbonyl]-L-leucyl-L-tyrosyl-6-aminohexanoyl-N6-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-lysinamide; Ethyl (2S,3S)-3-(((4S,7S,17S)-17-Carbamoyl-7-(4-hydroxybenzyl)-2-methyl-5,8,15,23-tetraoxo-27-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,16,22-tetraazaheptacosan-4-yl)carbamoyl)oxirane-2-carboxylate
CAS Number:314263-42-8
Molecular Formula:C₄₃H₆₆N₈O₁₁S
Molecular Weight:903.1
Category:Standards; Molecular Biology;
Applications:DCG04 is useful for the development of an isotope-coded activity-based probe for quantitative profiling of cysteine proteases. It is useful in receptor-mediated targeting of cathepsins in professional antigen presenting cells. It is also applied in chemical approaches for functionally probing the proteome.
References:van Swieten, P. F., et al.: Bioorg. Med. Chem. Lett., 14, 3131 (2004); Greenbaum, D., et al.: Mol. Cell. Proteomics, 1, 60 (2002); Hillaert, U., et al.: Angew. Chem. Int. Ed., 48, 1629 (2009)
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