Apixaban Potassium Formate Salt

Chemical Name:Apixaban Potassium Formate Salt
Synonyms:Apixaban Impurity 2; Potassium 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-5-carboxylate;
Alternate CAS #:503612-47-3
Molecular Formula:C₂₅H₂₆KN₅O₅
Molecular Weight:515.6
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Apixaban Potassium Formate Salt is an impurity of Apixaban (503612-47-3 #CAS), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References:Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);
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