CAS:1580491-20-8|2,5-Dioxopyrrolidin-1-yl hexyl Carbonate

Catalogue Number:D195655
Chemical Name:2,5-Dioxopyrrolidin-1-yl hexyl Carbonate
Synonyms:2,​5-​Dioxo-​1-​pyrrolidinyl Hexyl Carbonic Acid
CAS Number:1580491-20-8
Molecular Formula:C₁₁H₁₇NO₅
Molecular Weight:243.26
Solubility:Dichloromethane; Methanol
Category:Building Blocks; Miscellaneous;
Applications:2,5-Dioxopyrrolidin-1-yl hexyl Carbonate is an intermediate in the synthesis of 2-[[[4-[(Z)-Amino[[(hexyloxy)carbonyl]imino]methyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid (A611088), a degradation product of Dabigatran (D100090). which is a drug that is a nonpeptide, direct thrombin inhibitor and an antithrombotic.
References:Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)
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