CAS:1197196-48-7|N-Debenzyl-N-methyl-O-demethyl-O-(3-dimethylaminopropyl)-BIX 01294

Catalogue Number:D204075
Chemical Name:N-Debenzyl-N-methyl-O-demethyl-O-(3-dimethylaminopropyl)-BIX 01294
Synonyms:7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine; UNC 0224
CAS Number:1197196-48-7
Molecular Formula:C₂₆H₄₃N₇O₂
Molecular Weight:485.67
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Debenzyl-N-methyl-O-demethyl-O-(3-dimethylaminopropyl)-BIX-01294, is selective G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor.
References:Liu, F. et al.: J. Med. Chem., 53, 5844 (2010); Kubicek, S. et al.: Mol. Cell., 25, 473 (2007); Huangfu, D et al.: Nat. Biotechnol., 26, 795 (2008); Chang, Y. et al.: Bat. Struct. Mol. Biol., 16, 312 (2009);
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