CAS:444717-20-8|1-(2′-Deoxy-5′-O-DMT-3′-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine

Catalogue Number:D210870
Chemical Name:1-(2′-Deoxy-5′-O-DMT-3′-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine
Synonyms:1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-beta-D-threo-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
CAS Number:444717-20-8
Molecular Formula:C37H35N3O11S
Appearance:Light Orange to Orange Solid
Melting Point:>99°C (dec.)
Molecular Weight:729.75
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Applications:1-(2′-Deoxy-5′-O-DMT-3′-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine (CAS# 444717-20-8) is an intermediate in the synthesis of 3-N-Boc-5′-O-DMT-3′-O-Nosyl Thymidine (N212160), used in the radio-synthesis of 18F-labeled deoxyfluorothymidine as radiopharmaceutical for PET by fluorination via nucleophilic substitution of precursor.
References:Prochazka, L., et al.: Chemicke Listy, 102, 992-996 (2008);
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