CAS:144875-23-0|O-Desethyl Resiquimod

Catalogue Number:D228575
Chemical Name:O-Desethyl Resiquimod
Synonyms:4-Amino-2-(hydroxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol;
CAS Number:144875-23-0
Molecular Formula:C₁₅H₁₈N₄O₂
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:269-275°C
Molecular Weight:286.33
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:O-Desethyl Resiquimod is derived from its parent compound Resiquimod (R144680), which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References:Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);
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