CAS:1430804-85-5|5,6-Dehydro-17b-dutasteride

Catalogue Number:D229560
Chemical Name:5,6-Dehydro-17b-dutasteride
Synonyms:(4aR,4bS,6aS,7S,9aS,9bS)-N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10-dodecahydro-4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxamide; Dutateride EP Impurity G
Impurity:Dutateride EP Impurity G
CAS Number:1430804-85-5
Molecular Formula:C₂₇H₂₈F₆N₂O₂
Appearance:White to Off-White Solid
Melting Point:>171°C (dec.)
Molecular Weight:526.51
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Steroids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5,6-Dehydro-dutasteride (Dutateride EP Impurity G) is an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5a-reductase isoenzymes type 1 and 2
References:Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),
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