Apricoxib-d4

Chemical Name:Apricoxib-d4
Synonyms:4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide-d4; 4-Methyl-2-(4-ethoxyphenyl)-1-(4-sulfamoylphenyl)pyrrole-d4; CS 706-d4; R 109339-d4; TG 01-d4;
Molecular Formula:C₁₉H₁₆D₄N₂O₃S
Appearance:No data available
Melting Point:No data available
Molecular Weight:360.46
Solubility:No data available
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Apricoxib-d4, is the labeled analogue of Apricoxib (A729850), which is active, selective COX-2 inhibitor, used as as an analgesic and anti-inflammatory agent, and also has anticancer potential, since COX-2 inhibition can reduce tumor growth and augment therapy.
References:Kirane, A, et al.: Clinical Cancer Res., 18, 5031 (2012); Rohatagi, Sh., et al.: British J. Clin. Pharmaco., 66, 60 (2008);
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