CAS:895571-79-6|3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione

Catalogue Number:D235185
Chemical Name:3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione
Synonyms:6-Oxo-M1dG; Pyrimido[1,2-a]purine-6,10-dione, 3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,4-dihydro-(9CI); 3-(2-Deoxy-b-D-erythropentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione
CAS Number:895571-79-6
Molecular Formula:C₁₃H₁₃N₅O₅
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:>221°C (dec.)
Molecular Weight:319.27
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly, Heated)
Stability
Hygroscopic, Not stable in basic solution, Not Stable In Basic Solution
Category:Research Tools; Molecular Biology;
Applications:3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione is likely an endogenous biomarker in humans and is readily generated from M1dG in liver cytosol, which involves xanthine oxidase and aldehyde oxidase.
References:Otteneder, M.B.; et al.: Proc. Natl. Acad. Sci. U.S.A., 103, 6665 (2006)
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