Catalogue Number:D281940
Chemical Name:Dermorphin Trifluoroacetic Acid Salt
Synonyms:L-Tyrosyl-D-alanyl-L-phenylalanylglycyl-L-tyrosyl-L-prolyl-L-serinamide Trifluoroacetate; Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 TFA Salt;
CAS Number:78331-26-7
Alternate CAS #
freebase: 77614-16-5
Molecular Formula:C₄₀H₅₀N₈O₁₀ • C₂HF₃O₂
Appearance:White to Off-White Solid
Melting Point:157-162°C
Molecular Weight:802.87 + 114.02
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Amino Acids; Amino Acids/Peptides; Neurochemicals;
Applications:Dermorphin is a hepta-peptide and a natural opioid initially isolated from the skin of South American hylid frogs Phyllomedusinae. Dermorphin binds as an agonist with high potency and selectivity to mu-opioid receptors. Dermorphin is about 30-40 times more potent than Morphine.
References:Erspamer, V. et al.: Proc. Nat. Acad. Sci. U.S.A., 86, 5188 (1989); Negri, L. et al.: Hand. Biol. Act. Pep., 268 (2006); Broccardo, M. et al.: Br. J. Pharmacol., 73, 625 (1981);
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Posted inMaterials
CAS:78331-26-7|Dermorphin Trifluoroacetic Acid Salt
