CAS:403848-30-6|3-Desaminosulfonyl 2-Aminosulfonyl N-Acetyl Dorzolamide

Catalogue Number:D288115
Chemical Name:3-Desaminosulfonyl 2-Aminosulfonyl N-Acetyl Dorzolamide
Synonyms:(4S,6S)-4-(Acetylethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonyl Chloride 7,7-Dioxide;
CAS Number:403848-30-6
Molecular Formula:C₁₂H₁₆ClNO₅S₃
Molecular Weight:385.91
Category:Building Blocks; Miscellaneous;
Applications:3-Desaminosulfonyl 2-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate used in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100).
References:Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)
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