CAS:571190-22-2|6-Desacetyl Palbociclib

Catalogue Number:D288718
Chemical Name:6-Desacetyl Palbociclib
Synonyms:8-Cyclopentyl-5-methyl-2-[[(5-piperazin-1-ylpyridin-2-yl)]amino]-8H-pyrido[2,3-d]pyrimidin-7-one;
CAS Number:571190-22-2
Molecular Formula:C₂₂H₂₇N₇O
Appearance:Light Yellow Solid
Melting Point:>200ºC (dec.)
Molecular Weight:405.5
Storage:-20°C
Solubility:Acetonitrile (Slightly), Chloroform (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Desacetyl Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
References:Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);
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