CAS:56271-94-4|Descarbamoyl Cefuroxime

Catalogue Number:D288830
Chemical Name:Descarbamoyl Cefuroxime
Synonyms:(6R,7R)-7-[[(2Z)-2-(2-Furanyl)-2-(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Cefuroxime Sodium Impurity F (EP); Cefuroxime Sodium EP Impurity A;
Impurity:Cefuroxime Sodium EP Impurity A
CAS Number:56271-94-4
Molecular Formula:C₁₅H₁₅N₃O₇S
Appearance:White to Pale Beige Solid
Melting Point:>135°C (dec.)
Molecular Weight:381.36
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:Descarbamoyl Cefuroxime (Cefuroxime Sodium EP Impurity A) is a degradation product of Cefuroxime, and an intermediate for the synthesis of Cephalosporin antibiotics
References:Nomura, H., et al.: J. Med. Chem., 17, 12 (1974), Takaya, T., et al.: J. Antibiotics, 34, 1300 (1981), Wang, D., et al.: J. Pharm. Sci., 83, 577 (1994), Okamoto, Y., et al.: J. Pharm. Sci., 85, 985
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