tert-Butyl (1S,3R,4R)-3-(6-(4,4,5,5,-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate

Chemical Name:tert-Butyl (1S,3R,4R)-3-(6-(4,4,5,5,-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
Synonyms:Ledipasvir Impurity 3
Molecular Formula:C₂₄H₃₄BN₃O₄
Molecular Weight:439.36
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:tert-Butyl (1S,3R,4R)-3-(6-(4,4,5,5,-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate can be obtained from (R)-(+)-α-Methylbenzylamine (M288800) which can be used as reactant/reagent in synthesis of urea-containing peptide boronic acids as proteasome inhibitors.
References:Han, L., et al.: Eur. J. Med. Chem., 125, 925-939 (2017)
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