CAS:1430844-80-6|A-1331852

Catalogue Number:A100900
Chemical Name:A-1331852
Synonyms:6-[8-[(2-Benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-3-[5-methyl-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazol-4-yl]-2-pyridinecarboxylic Acid
CAS Number:1430844-80-6
Molecular Formula:C₃₈H₃₈N₆O₃S
Appearance:Pale Yellow to Light Beige Solid
Melting Point:>161ºC (dec.)
Molecular Weight:658.81
Storage:-20°C
Solubility:Acetonitrile (Slightly, Heated), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A-1331852 is a substituted benzothiazole that can serve as an anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent useful in the treatment of cancer, immune and autoimmune diseases.
References:Wang, L., et al.: PCT Int. Appl. WO 2013055897 A1 20130418. Apr 18, 2013
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