(E)-Cefpodoxime Proxetil-d3

Chemical Name:(E)-Cefpodoxime Proxetil-d3
Synonyms:(6R,7R)-7-[[(2E)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-[[(1-Methylethoxy)carbonyl]oxy]ethyl Ester-d3
Alternate CAS #:Unlabelled: 947692-13-9
Molecular Formula:C₂₁H₂₄D₃N₅O₉S₂
Molecular Weight:560.62
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:(E)-Cefpodoxime Proxetil-d3 is the isotope labelled analog of (E)-Cefpodoxime Proxetil (C243855); the (E)-isomer of Cefpodoxime Proxetil (C243860) which is an antibacterial and broad spectrum, orally absorbed third generation cephalosporin. The (E)-isomer tends to have less antibacterial activity than the (Z)-isomer.
References:Fujimoto, K., et al.: J. Antibiot., 40, 370 (1987); Utsui, Y., et al.: Antimicrob. Agents Chemother., 31, 1085 (1987); Rajadurai, R., et al.: Anal. Chem.: Ind. J., 9, 265 (2010)
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