CAS:1379005-34-1|N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide

Catalogue Number:A167620
Chemical Name:N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide
Synonyms:N-​Acetyl-​N-​[2-​(7-​methoxy-​1-​naphthalenyl)​ethyl]​acetamide; Agomelatine Impurity 7; Agomelatine Diacetyl Impurity:Impurity:Agomelatine Diacetyl Impurity / Agomelatine Impurity 7
CAS Number:1379005-34-1
Molecular Formula:C₁₇H₁₉NO₃
Appearance:White to Off-White Solid
Melting Point:104 – 106°C
Molecular Weight:285.34
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide is an impurity of Agomelatine (A430000), a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. (Agomelatine Impurity 7)
References:Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),
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