CAS:51370-03-7|7-​(Acetyloxy)​-​2-​chloro-dibenz[b,​f]​[1,​4]​oxazepin-​11(10H)​-​one

Catalogue Number:A187433
Chemical Name:7-​(Acetyloxy)​-​2-​chloro-dibenz[b,​f]​[1,​4]​oxazepin-​11(10H)​-​one
Synonyms:2-Chloro-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepin-7-yl Acetate
CAS Number:51370-03-7
Molecular Formula:C₁₅H₁₀ClNO₄
Appearance:Gray Solid
Molecular Weight:303.7
Solubility:DMSO
Category:Standards; Miscellaneous;
Applications:7-​(Acetyloxy)​-​2-​chloro-dibenz[b,​f]​[1,​4]​oxazepin-​11(10H)​-​one is an intermediate in synthesizing 7-Hydroxy Loxapine (H943790), a metabolite of Loxapine (L472750), a neuroleptic medication used to treat patients with schizophrenia and obsessive compulsive disorder.
References:Kapur, S., et al.: Am. J. Psychiatry, 154, 1525 (1997); Rivers-Bulkeley, N. & Hollender, M.: Am. J. Psychiat., 139, 1345 (1982)
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