CAS:4991-55-3|(6a,11b,16a)-21-(Acetyloxy)-9-bromo-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

Catalogue Number:A187773
Chemical Name:(6a,11b,16a)-21-(Acetyloxy)-9-bromo-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Synonyms:2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole Pregna-1,4-diene-3,20-dione Derivative; 9-Bromo-6α-fluoro-11β,16α,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione 21-acetate Cyclic 16,17-acetal with Acetone;
CAS Number:4991-55-3
Molecular Formula:C₂₆H₃₂BrFO₇
Appearance:Pale Yellow Solid
Molecular Weight:555.43
Solubility:Chloroform, Methanol
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(6a,11b,16a)-21-(Acetyloxy)-9-bromo-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione is an intermediate in synthesizing Flunisolide (F500485), which is a synthetic fluorinated corticosteroid related to Prednisolone (P703740). Antiasthmatic.
References:Chu, N.I., et al.: Drug Metab. Dispos., 7, 81 (1979), Pakes, G.E., et al.: Drugs, 19, 397 (1980);
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