(R)-3′-[[2-[[2-(3-Chlorophenyl)-2-[[(tert-butyl)dimethylsilyl]oxy]ethyl][(tert-butoxy)carbonyl]amino]ethyl]amino]-[1,1′-biphenyl]-3-carboxylic Acid Methyl Ester

Chemical Name:(R)-3′-[[2-[[2-(3-Chlorophenyl)-2-[[(tert-butyl)dimethylsilyl]oxy]ethyl][(tert-butoxy)carbonyl]amino]ethyl]amino]-[1,1′-biphenyl]-3-carboxylic Acid Methyl Ester
Synonyms:3′-[[2-[[(2R)-2-(3-Chlorophenyl)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl][(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]-[1,1′-biphenyl]-3-carboxylic Acid Methyl Ester
CAS Number:252921-55-4
Molecular Formula:C₃₅H₄₇ClN₂O₅Si
Molecular Weight:639.3
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(R)-3′-[[2-[[2-(3-Chlorophenyl)-2-[[(tert-butyl)dimethylsilyl]oxy]ethyl][(tert-butoxy)carbonyl]amino]ethyl]amino]-[1,1′-biphenyl]-3-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Solabegron Hydrochloride (S676510). Solabegron Hydrochloride is a selective β3-adrenergic receptor agonist, that also produces Somatostatin (S676750). This drug is used for the treatment of irritable bowel syndrome.
References:Grudell, A., et al.: Am J Physiol, 294, G1114 (2008)
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