CAS:850140-72-6|Afatinib

Catalogue Number:A355300
Chemical Name:Afatinib
Synonyms:(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992;
CAS Number:850140-72-6
Molecular Formula:C₂₄H₂₅ClFN₅O₃
Appearance:White to Pale Yellow Solid
Melting Point:>140ºC (dec.)
Molecular Weight:485.94
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Sonicated)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:An aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
References:Nakao, K., et al.: Sci. Rep., 9, 18202 (2019); Ebert, K, PLoS One, 14, 0223225 (2019)
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